The VNUS Closure procedure is a minimally invasive treatment alternative to traditional vein stripping surgery for venous reflux, a common underlying cause of varicose veins. The VNUS Closure procedure system was cleared for marketing in the US in March 1999. The Closure procedure by VNUS is becoming increasingly popular as doctors become more familiar with this treatment. The procedure is done by placing a very small tube (catheter) into the vein to deliver radiofrequency energy to the vein wall, causing it to collapse and seal shut. Once the diseased vein is sealed, healthy veins will take over and redirect the blood flow.

The Closure procedure by VNUS is minimally invasive and can be performed under local anesthesia in a doctor's office. Patients have reported feeling little, if any, pain during the procedure and most return to their normal activity within a day. Some common side effects may include temporary tenderness and numbness. Most patients report a noticeable improvement in their symptoms in 1-2 weeks following the procedure and experience good cosmetic outcomes with little to no pain, scarring, or bruising.

The VNUS Closure procedure is covered by most insurance companies, when deemed medically necessary.